Skip to Main Content
Brown University
The Warren Alpert Medical School

Department of Emergency Medicine

Secondary Navigation Navigation

  • Give Now
Search Menu

Site Navigation

  • Home
  • About
    • Clinical Sites
    • Programs
  • Faculty Affairs
    • Meet Our Faculty
    • Wellness
    • Faculty Development
  • Education
    • Residency Program
    • Fellowships
    • EMPAT
    • EMAT
    • Medical Students
  • Divisions
    • Disaster Medicine
    • Emergency Medical Services (EMS)
    • Global Emergency Medicine
    • Injury Prevention
    • Medical Simulation
    • Ultrasound
    • Emergency Department Operations & Quality Improvement
    • Social Emergency Medicine
  • Research
    • Current Funding
    • Research Sites, Centers & Labs
  • Health Equity
    • Residency Culture
    • Diversity Visiting Student Scholarship
    • WoBEM
    • BPI Diversity & Inclusion
    • Office of Belonging, Equity, Diversity, and Inclusion at Brown
  • Pediatric Emergency Medicine
Search
Department of Emergency Medicine

Research

The department has a diverse and successful research enterprise with two basic science laboratories and a full infrastructure to support clinical research.

Sub Navigation

  • Current Funding
  • Research Sites, Centers & Labs
blue and purple swirling graphic

Advance Clinical and Translational Research

Advance-CTR supports Rhode Island investigators through funding, research resources and services, and professional development offerings.

Advance-CTR

Research

The department has a diverse and successful research enterprise with two basic science laboratories and a full infrastructure to support clinical research.

A Message from Research

Welcome to the research webpage for the Department of Emergency Medicine at Brown University/ Brown Emergency Medicine! Our department is a national leader in emergency medicine research, and we aim to generate and translate knowledge that will improve the lives of our patients and communities. Our faculty and residents conduct research across a wide range of topics including injury prevention, global health, health equity and population health, acute cerebrovascular disease, sex and gender medicine, trauma, sepsis, substance use and harm reduction, point of care ultrasound, and degenerative joint disease, among others. We have a robust infrastructure to support clinical research in our department, and we collaborate with investigators across departments and other institutions, locally, regionally, and nationally.

 

 

Research Program Members

NameTitle
 Vice Chair of Research
Taneisha Wilson, MD, MPHClinical Director of Research
Gregory Jay, MD, PhDEmeritus Director of Research
Kirsten Langdon, PhDDirector of Research Innovation
Siraj Amanullah, MD, MPHDirector of Resident Research
Tom Chun, MD, MPHDirector of Research, Division of Pediatric Emergency Medicine
Maris Sangamang, MA, MPHSenior Research Administrator
Erin Ryan, MPH, CCRPSenior Research Administrator
Mike SavageAdministrative Coordinator
Carolyn Ortega, MPHResearch Program Manager
Samuel KaplanSr. Clinical Research Assistant
Ashley GaipoRegulatory Coordinator
Sarah TokarzClinical Research Program Coordinator
Mhina Johnbaptiste, MPHClinical Research Program Coordinator
Fatimah LawalClinical Research Assistant
Hailey GallegosClinical Research Assistant
Mia O'LearyClinical Research Assistant
Sarah RussoClinical Research Assistant
Jackson DeMartinoClinical Research Assistant
David BishopClinical Research Assistant
Victoria (Tori) BeckClinical Research Assistant
Devany RoesslerClinical Research Assistant

Data Science Team

Name Title
Janette Baird, PhD Senior Research Scientist
Timmy Lin, MPH Data Analyst
Troy (Chuyun) Xu, MPH Data Coordinator/Analyst

Research Announcements

TAP Study Coming to RIH

Trauma is the leading cause of death in those under the age of 45. The most common cause of preventable death after injury is bleeding, which is often accompanied by clotting factor abnormalities.

Kcentra® (or 4-factor prothrombin complex concentrate) is a Food and Drug Administration (FDA) approved product that contains clotting factors. It is currently used to reverse the effects of medications given to “thin” the blood in patients, when such patients experience bleeding and/or require surgery.

There is evidence that Kcentra® may be beneficial (reduce the chance of dying) in injured patients who are not on blood-thinning medication. The TAP trial is a research trial to see whether Kcentra reduces the chances of injured people dying from their injuries. The aim of the Trauma and PCC (TAP) trial is to formally evaluate the effectiveness of Kcentra®, in addition to all standard care, in injured patients predicted to require a large volume blood transfusion. Standard care typically involves the transfusion of different types of blood products, and the use of medications to help the blood clot (as well as surgery, to stop the bleeding). Because Kcentra must be administered quickly to possibly help patients and most patients cannot consent to a study soon after a serious injury, most patients will be enrolled without their consent.

TAP is one of the largest trauma trials ever conducted. It will involve up to 8,000 patients, across 140 hospitals (around 100 of them in the United States, the remainder in a small number of other countries).

Our department is a site for TAP and will be enrolling patients using an EFIC (exception from informed consent) protocol (see more info at the link below). Site PI is Dr Stephanie Lueckel with Dr. Greg Jay and Dr Selim Suner as Co-Investigators.

TAP Study

PROMPT Bolus is also currently enrolling

(EFIC) research project post-enrollment public disclosure plan

RIH, a site for PECARN, a national multi-site clinical trials network, is currently enrolling for PROMPT-Bolus, an EFIC study. The objectives of this multicenter Phase 3 pragmatic clinical trial are to compare the effectiveness and relative safety of balanced fluid resuscitation versus 0.9% normal saline in children with septic shock, including whether balanced fluid resuscitation can reduce progression of kidney injury. Site PI is Dr. Susan Duffy.

Visit the Brown University Health website for more details about this study.

PECARN Prompt Bolus Study

blue and purple swirling graphic

Advance Clinical and Translational Research

Advance-CTR supports Rhode Island investigators through funding, research resources and services, and professional development offerings.

Advance-CTR
Brown University
Providence RI 02912 401-863-1000

Quick Navigation

  • Division of Biology and Medicine
  • Program in Biology
  • Affiliated Hospitals

Footer Navigation

  • Events
  • Maps and Directions
  • Contact Us
  • Accessibility
Give To Brown

© Brown University

The Warren Alpert Medical School
For You
Search Menu

Mobile Site Navigation

    Mobile Site Navigation

    • Home
    • About
      • Clinical Sites
      • Programs
    • Faculty Affairs
      • Meet Our Faculty
      • Wellness
      • Faculty Development
    • Education
      • Residency Program
      • Fellowships
      • EMPAT
      • EMAT
      • Medical Students
    • Divisions
      • Disaster Medicine
      • Emergency Medical Services (EMS)
      • Global Emergency Medicine
      • Injury Prevention
      • Medical Simulation
      • Ultrasound
      • Emergency Department Operations & Quality Improvement
      • Social Emergency Medicine
    • Research
      • Current Funding
      • Research Sites, Centers & Labs
    • Health Equity
      • Residency Culture
      • Diversity Visiting Student Scholarship
      • WoBEM
      • BPI Diversity & Inclusion
      • Office of Belonging, Equity, Diversity, and Inclusion at Brown
    • Pediatric Emergency Medicine

Mobile Secondary Navigation Navigation

  • Give Now
All of Brown.edu People
Advanced Search
Close Search

Research